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Chromium History

The history behind chromium, an essential mineral
Since the 1950s, it’s been known that trivalent chromium is a trace mineral needed by the body in order for insulin to properly use glucose. It wasn’t until April 1977, when Toronto General Hospital’s Khursheed N. Jeejeebhoy, Ph.D., published a landmark study in the American Journal of Clinical Nutrition that chromium was firmly established as critical for human health. In this study, when a patient, who had been receiving total parenteral nutrition (TPN) feedings for over five years, was given chromium in her intravenous feedings, her symptoms of chromium deficiency and blood-sugar imbalance were all “corrected or restored to their previous levels.” These findings influenced the U.S. Food and Nutrition Board to designate chromium as “essential for human health.”

Insulin, which is truly a master hormone of our metabolism, keeps glucose levels balanced, regulates the body’s utilization of carbohydrates, fats and protein for energy, and is thought to directly affect certain genetic metabolic processes. Overall, chromium helps the body’s tissues respond efficiently to insulin. Unfortunately, however, people tend to lose chromium as they age, after strenuous exercise, and after eating high sugar foods.

The typical American diet, high in refined foods such as flour and sugar, supplies little chromium. In addition, many Americans tend not to eat foods rich in chromium, such as organ meats, mushrooms, broccoli, brewer’s yeast, brown rice, cheese, meat and wheat germ.

The average American only gets 35 mcg a day of chromium (which is the Dietary Reference Intake, or DRI). A person would need to eat as much as 12 turkey legs or 50 egg bagels each day to get the USDA’s recommended daily intake (Reference Daily Intake, or RDI) set for chromium of 120 mcg. Considering that the clinical body of evidence suggests that 200 to 400 mcg per day are needed to achieve optimal health benefits, the DRI may prove inadequate, especially in people who are insulin resistant.

Establishing baselines & determining bioavailability of chromium
Researchers from Harvard University’s School of Public Health are currently conducting a study that should provide baseline results determining and comparing chromium levels in healthy people and in people with diabetes using what is perhaps the body’s most reliable gauge—the levels of chromium present in a person’s toenails. These results, and others available this year, should provide better clinical and therapeutic baselines and bioavailability measurement guides that will influence our future research efforts. Future initiatives will provide a better understanding of why, for example, certain groups of people respond very well to chromium supplementation (women) while others don’t respond as dramatically (elite athletes). Upcoming US Department of Agriculture (USDA)-sponsored studies will also provide even further corroboration as to the greater efficacy and bioavailability of chromium picolinate over other forms of this essential mineral.



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