Brain Health Supplement for the 78 Million Baby Boomers
Who Rate Cognitive Decline as a Top Concern

PURCHASE, N.Y., November 5, 2007 – Nutrition 21, Inc. (NASDAQ: NXXI), a leading developer and marketer of chromium-based and omega-3 fish oil-based nutritional supplements, today announced the availability of a new nutritional supplement, Core4Life™ Advanced Memory Formula™. The supplement contains a unique combination of chromium picolinate, phosphatidylserine (PS) and DHA, ingredients that all play an important role in helping improve memory and maintain brain health.   

Forgetfulness increases with age and U.S. Baby Boomers – 78 million strong – rate cognitive function decline as a top concern (along with having enough money for retirement) . As the brain ages, brain cells dry out and shrink, connections between nerve cells slow and blood circulation and nutrient flow to the brain decrease – all of which can affect cognition. Recent research has also linked impaired glucose metabolism or insulin resistance in the brain to dementia and Alzheimer’s disease , .  Core4Life Advanced Memory Formula contains the nutrients PS and DHA to help lubricate and increase communication between brain cells and chromium picolinate to increase glucose metabolism, which allows glucose – the brain’s main “fuel” – to be processed more efficiently. 

“Improved memory, mind and brain function are among the highest-rated end benefits that consumers seek in health products. This is especially true for millions of Baby Boomers who are living significantly longer and beginning to experience the inevitable onset of cognitive decline that comes naturally with age,” said Paul Intlekofer, President and CEO of Nutrition 21. “With Core4Life Advanced Memory Formula, we have identified an unmet need in the retail marketplace which is supported by emerging research.  As with all of our products, we’ve taken a scientific approach to the development of Core4Life Advanced Memory Formula by combining nutrients that are essential to improving and maintaining brain health.”

Feeling forgetful? 
A new survey of Lost and Found Departments in seven urban public transportation systems with big Boomer populations shows that people can lose track of items that are both indispensable and irrelevant.  While the top five list was not a surprise (wallets, cell phones, purses, glasses and keys), intriguing regional differences emerged:
- Are New Yorkers more tech-dependent than other cities? Ipod/MP3s and PDAs were in New York City’s top five. 
- Tampa’s geography and older demographic made sunglasses and prescription medications among that sunny city’s top five. 
- The rainy Northwest: Portland’s top five included umbrellas.
- Dallas transit riders brown bag it: lunch bags made the top five in the Big D.
- Lost bikes made the top five in Providence, RI and San Antonio, TX, which begs the question, why were these people on public transit? 
- Indianapolis is for bookworms: forgotten books made the top five in the Racing Capital of the World. (Hope they didn’t belong to the library!)
- Strangest lost items included dentures, a weed eater, an oxygen tank, a set of bowling balls and shoes, a vacuum cleaner and used underwear.

About Core4Life Advanced Memory Formula
Core4Life Advanced Memory Formula, available in soft gel form, contains a proprietary blend of chromium picolinate, PS and DHA. These ingredients have been scientifically tested for their ability to improve cognitive function:
- Chromium picolinate is an essential trace mineral that promotes healthy blood sugar, which is important because glucose helps fuel our brain.
- PS is a naturally occurring phospholipid nutrient essential to the functioning of all cells of the body, but is most concentrated in the brain. PS supports communication between brain cells and promotes improved memory.
- DHA is an omega-3 fatty acid, most commonly found in fish oil, which maintains brain fluidity and may help in the maintenance of cognitive function.

Core4Life Advanced Memory Formula is manufactured according to strict Food and Drug Administration (FDA) guidelines. This product can be taken safely alone or with medication, with optimal results seen in 30 to 90 days. In addition, the chromium picolinate ingredient is deemed safe by the FDA and is Generally Recognized as Safe (GRAS) for use in foods and supplements.

Core4Life Advanced Memory Formula is available at major retailers nationwide in the vitamin section. For more information about Core4Life Advanced Memory Formula visit www.core4life-amf.com.

About Nutrition 21
Nutrition 21, Inc. (NASDAQ: NXXI), headquartered in Purchase, NY, is a nutritional bioscience company and the maker of chromium picolinate-based and omega-3 fish oil-based supplements with health benefits substantiated by clinical research. Nutrition 21 holds more than 30 patents for nutrition products and uses. Nutrition 21’s portfolio of health and wellness brands include: Chromax®, Core4Life™ Advanced Memory Formula™, Diabetes Essentials™, Iceland Health® Maximum Strength Omega-3 and Iceland Health® Joint Relief. The company also manufactures private label supplements and ingredients for third parties. Nutrition 21 distributes its products nationally through more than 29,000 major food, drug and super center retailers as well as internationally.  For more information please visit http://www.nutrition21.com.
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[4] Survey was conducted by Fleishman-Hillard, Inc. on behalf of Nutrition 21, Inc. between October 10 and October 19, 2007 among seven public transportation departments in the United States: Providence, Tampa, San Antonio, Indianapolis, Dallas, New York and Portland.